The Andromeda Strain by Michael Crichton.
Ballantine Books, 1993 (1969).
Certainly the Wildfire team was under severe stress, but they were also prepared to make mistakes. They had even predicted that this would occur. What they did not anticipate was the magnitude, the staggering dimensions of their error. They did not expect that their ultimate error would be a compound of a dozen small clues that were missed, a handful of crucial facts that were dismissed.
— From Chapter 24, The Andromeda Strain
Michael Crichton’s 1969 techno-thriller is in some ways an update of H G Wells’ The War of the Worlds, but instead of invading Martians being defeated by a earth-borne microbes (or “putrefactive and disease bacteria” as Wells has it, our “microscopic allies”) here it is the extraterrestrial microscopic organisms that threaten humankind. Brought back to earth by a Project Scoop satellite, they kill human beings by almost instantly clotting their blood. A top secret team codenamed Wildfire is tasked with retrieving, analysing, assessing and counteracting this virulent invader before it spreads to the general population. Holed up in an underground lab, they have a scant few days to come up with solutions; this being a thriller, things do not go smoothly.
Put thus baldly The Andromeda Strain appears to be a fairly humdrum novel, its premise familiar from scores of dystopic novel plotlines and SFF films and TV series. But, bearing in mind the date of its release — at the height of a flurry of manned space missions (though just three years from the last Apollo mission to the moon) and on the crest of a wave of optimism in the march of science and technology in the face of Cold War tensions — its then impact isn’t hard to imagine. The nightmare scenario of an invisible killer chimed in with fears of Russian aggression — remember, the USSR and its Warsaw Pact allies had in 1968 invaded Czechoslovakia, a country at the heart of Europe. While the US became more mired in a disastrous Vietnam conflict, despite opposing a technologically poorer nation, on the other hand it had sent a mission around the moon; and computer sciences seemed to be announcing new advances on a daily basis.